Progressive disseminated histoplasmosis presenting like chronic parenchymal liver disease with ascites: a rare case report and discussion

A 82 year old diabetic and hypertensive Muslim man presented with ascites along with features of portal hypertension. Though it initially seemed to be a primary case of chronic parenchymal liver disease, investigations revealed it to be a case of Progressive Disseminated Histoplasmosis (PDH) with bilateral adrenomegaly, hepatosplenomegaly and ascites. The ascites was high SAAG in nature and no evidence of malignancy or tuberculosis could be found. The patient was treated with liposomal amphotericin B and was subsequently discharged on oral itraconazole therapy. On follow-up he was found to be significantly better at 3 months.

Why do Low R2 Hedge Funds have Low R2? An Empirical Study of the Performance and Risk of Low R2 Funds

In this study, I examine whether low R2 funds are exposed to higher equity systematic tail risk that is not accounted for in the existing multi-factor models used to evaluate hedge funds. With a parsimonious set of risk factors that includes systematic tail risk, I show that there is a significant increase (about 12%) in the R2 for funds in the lowest quintile of R2. In contrast, the increase in R2 for funds in the other quintiles of R2 is relatively modest (about 2%). Moreover, I show that the spreads between the future performance of low and high R2 funds narrows by about 9% after accounting for the systematic tail risk factor. I also show that 90% of the decrease in future performance spread is driven by accounting for tail risk in the low R2 funds. My results provide evidence that superior performance of low R2 funds may not be entirely attributable to higher managerial skill, and that systematic tail risk of such funds can partially explain why they perform well

Oscillating Shells and Oscillating Balls in AdS

It has recently been reported that certain thin timelike shells undergo oscillatory motion in AdS. In this paper, we compute two-point function of a probe field in the geodesic approximation in such an oscillating shell background. We confirm that the two-point function exhibits an oscillatory behaviour following the motion of the shell. We show that similar oscillatory dynamics is possible when the perfect fluid on the shell has a polytropic equation of state. Moreover, we show that certain ball like configurations in AdS also exhibit oscillatory motion and comment on how such a solution can be smoothly matched to an appropriate exterior solution. We also demonstrate that the weak energy condition is satisfied for these oscillatory configurations.Comment: 23 pages, 5 figures; v2: refs added; v3: JHEP versio